AFNI Message Board

Dear AFNI users-

We are very pleased to announce that the new AFNI Message Board framework is up! Please join us at:

https://discuss.afni.nimh.nih.gov

Existing user accounts have been migrated, so returning users can login by requesting a password reset. New users can create accounts, as well, through a standard account creation process. Please note that these setup emails might initially go to spam folders (esp. for NIH users!), so please check those locations in the beginning.

The current Message Board discussion threads have been migrated to the new framework. The current Message Board will remain visible, but read-only, for a little while.

Sincerely, AFNI HQ

History of AFNI updates  

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July 29, 2014 10:37AM
> I've tried to do a little bit more research and have discovered actually quite a few articles
> about resting-state connectivity in which they plot t-statistic maps instead of mean
> z-transformed correlations...

What is prevalent in the field does not necessarily mean such a practice should be treated as something carved in stone. I would argue that the colored maps should even present the correlation values (converted back from z-values through the inverse Fisher transformation). To support the argument, let me quote a paragraph I wrote elsewhere:

"A statistic (e.g., t-statistic) depends on the effect amplitude, signal-to-noise ratio, and sample size. As it has no physical dimension, a statistic only serves the purpose of a binary inference between null and alternative hypotheses, and reporting significance alone could render a distorted representation of reality. For example, two voxels (or regions) with the same t-statistic value in the brain do not mean the same response amplitude (or correlation), and vice versa. The distorted impression from the colored (and thresholded) statistic values was strongly evidenced in recent surveys (e.g, Engel and Burton, 2013). It is the response amplitude or effective size, not the thresholded statistic value, that should be the primary product of scientific investigation. The omnipresence (and over-obsession) of focus on only statistic values (color-coded blobs of t-values), while ignoring the effect magnitudes, leads to a situation where one would be unable to gauge the false negative rate (or power) of the study, the probability of failure (or success) to detect the effect. Activation identification in FMRI data analysis heavily relies on the contrasting between conditions; however, the contrast between a significant effect and a nonsignificant one is not necessarily statistically significant. The lopsided focus on statistical significance (e.g., peak definition based on statistic value) may enforce two prevalent fallacies: 1) the probability of obtaining the current data given the null is the same as that of the null given the data; and 2) if the result is not statistically significant, it proves that no effect exists."

Gang



Edited 2 time(s). Last edit at 07/29/2014 02:00PM by Gang.
Subject Author Posted

Seed correlation analysis in AFNI explained

afniuser July 24, 2014 11:31AM

Re: Seed correlation analysis in AFNI explained

rick reynolds July 25, 2014 08:43AM

Re: Seed correlation analysis in AFNI explained

afniuser July 29, 2014 02:52AM

Re: Seed correlation analysis in AFNI explained

rick reynolds July 29, 2014 10:13AM

Re: Seed correlation analysis in AFNI explained

gang July 29, 2014 10:37AM

Re: Seed correlation analysis in AFNI explained

umeshksingla June 03, 2018 04:24PM