AFNI Message Board

Dear AFNI users-

We are very pleased to announce that the new AFNI Message Board framework is up! Please join us at:

https://discuss.afni.nimh.nih.gov

Existing user accounts have been migrated, so returning users can login by requesting a password reset. New users can create accounts, as well, through a standard account creation process. Please note that these setup emails might initially go to spam folders (esp. for NIH users!), so please check those locations in the beginning.

The current Message Board discussion threads have been migrated to the new framework. The current Message Board will remain visible, but read-only, for a little while.

Sincerely, AFNI HQ

History of AFNI updates  

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March 25, 2015 05:17PM
Hi Anita,

Let me give you my opinion here, apart from Gang's advice. The magnitude of the signal changes greatly depend on BOLD sensitivity and magnetic field strength. Clearly, we expect larger signal changes at 7T than at 3T, and at 3T than at 1.5T, and so on. Furthermore, the BOLD sensitivity varies across regions depending on the magnitude of the change in transverse relaxation R2* (i.e. Delta R2*) due to the BOLD effect and also depend on the echo time. For instance, sensorimotor and visual cortices usually exhibit higher BOLD sensitivity than frontal areas.

To sum up, it depends on the task and field strength. For instance, we observed very large signal changes (> 5%) at 7T in a simple event-related visually cued finger tapping task.

An excellent reference is

van der Zwaag W, Francis S, Head K, Peters A, Gowland P, Morris P, Bowtell R. (2009) fMRI at 1.5, 3 and 7 T: characterising BOLD signal changes. Neuroimage. 2009 Oct 1;47(4):1425-34. doi: 10.1016/j.neuroimage.2009.05.015.

Hope this helps,
Cesar
Subject Author Posted

Reasonable Percent Signal Change Values

acservenka March 24, 2015 07:29PM

Re: Reasonable Percent Signal Change Values

gang March 25, 2015 12:31PM

Re: Reasonable Percent Signal Change Values

Cesar Caballero Gaudes March 25, 2015 05:17PM