The following is the README file for the permutation test plugins written by Matthew Belmonte. This code has been released under the GPL. ------------------------------------------------------------------------------ This directory contains plug_permtest.c and plug_threshold.c, source modules for the AFNI Permutation Test and Threshold plugins, respectively. The threshold plugin separates brain from non-brain (with touch-up work being handled by the Draw Dataset plugin), and the Permutation Test plugin evaluates activations for statistical significance using a sensitive, nonparametric algorithm. To build both modules, place them in your AFNI source code directory and type "make plug_permtest.so" and "make plug_threshold.so". If you use this software in your research, please take a moment to send mail to the author, belmonte@mit.edu, and cite the following paper in your report: Matthew Belmonte and Deborah Yurgelun-Todd, `Permutation Testing Made Practical for Functional Magnetic Resonance Image Analysis', IEEE Transactions on Medical Imaging 20(3):243-248 (2001). The permutation test takes a lot of memory and a lot of CPU. You'll want to use the fastest processor and system bus that you can lay your hands on, and at least 256MB of memory. If you're using Digital UNIX, you may find that the plugin will be unable to allocate all the memory that it needs unless you increase the values of the following kernel parameters: max-per-proc-address-space, per-proc-data-size, max-per-proc-data-size, per-proc-address-space, max-per-proc-address-space. To change these parameters, use the command-line tool "dxkerneltuner", or the graphical interface "sysconfig".