Hi Kate,

It might be more clear knowing your current
afni_proc.py command. But it looks like you
are removing both the average white matter
signal and the local white matter signal, and
that might be what is bothering you.

It is probably based on the help example, which
I *thought* I had updated, but it seems not,
sorry. The example was written that way both
as a demo of what one could do and because that
is what someone had done for their paper. But
it makes more sense to not do both local and
global WMe regression. So you might remove
'-regress_ROI FSWe'. I will do that now, too.

What that your concern?

- rick