Hello, As I described before, each session has 6 run.and a run has six times of five tastes stimulation.So each session has 6*6*5=180 trails.In addition,I collected four subjects fMRI data and each subject has the same five session.In subhect level, can I use 3dmema to make one sample t-test of five session results of each subjects,Is it a correct way or can you give me some right suggestion to get the individual level results using the five session results? Thanks you so much.I feel so bad to collect such data structure.