++ Compile date = Feb 25 2021 {AFNI_21.0.12:linux_ubuntu_16_64}

afni -no_detach -quiet -VAFNI_COMPRESSOR=
<BLANK>

afni -no_detach -quiet -VAFNI_AUTOGZIP=
YES

afni -no_detach -quiet -VAFNI_NOMMAP=
<BLANK>

time 3dROIstats -mask mask2.nii.gz func.nii.gz
File	Sub-brick	Mean_1  
func.nii.gz	0[?]	9957.563410
func.nii.gz	1[?]	9947.920665
func.nii.gz	2[?]	9938.978018
func.nii.gz	3[?]	9942.901682
...
func.nii.gz	335[?]	10079.657652
func.nii.gz	336[?]	10037.459720
func.nii.gz	337[?]	10058.559225

real	2m28.275s
user	2m14.740s
sys	0m13.461s

++ Compile date = Jan 29 2020 {AFNI_20.0.04:linux_ubuntu_16_64}

~/abin_older/afni -no_detach -quiet -VAFNI_COMPRESSOR=
<BLANK>

~/abin_older/afni -no_detach -quiet -VAFNI_AUTOGZIP=
YES

~/abin_older/afni -no_detach -quiet -VAFNI_NOMMAP=
<BLANK>

time ~/abin_older/3dROIstats -mask mask2.nii.gz func.nii.gz 
File	Sub-brick	Mean_1  
func.nii.gz	0[?]	9957.563410
func.nii.gz	1[?]	9947.920665
func.nii.gz	2[?]	9938.978018
...
func.nii.gz	335[?]	10079.657652
func.nii.gz	336[?]	10037.459720
func.nii.gz	337[?]	10058.559225

real	0m0.531s
user	0m0.475s
sys	0m0.056s