Rick, thank for the fast reply! I understand the need for a baseline here and the ambiguity issue. The original study was designed only to look at relative differences between conditions and not activation levels for any one condition per se. Given that 3dDeconvolve will still produce a beta for each condition, can you help me understand how to think about what that means? Does it make sense to think of it as deviation from a voxel-wise mean that includes the other two conditions?