¥ For individual subject thresholded activation
maps:
H Use
GLSQ/REML estimation, especially for slow block design experiments at 3+ Tesla
H Be aware
that there may be many false negatives
o i.e., false acceptances of
the null hypothesis
o am looking into an FDR-like
procedure for estimating the false negative rate, similar to how FDR estimates the false positive
rate
o
¥ For group maps using ANOVA (or similar statistics):
H Differences
between OLSQ and GLSQ estimation are small
H
¥ Recommendations:
H DonÕt need to re-visit group activation
conclusions!
H Use 3dREMLfit as a near drop-in replacment for 3dDeconvolve for future
work
oA little extra CPU time (usually from 1..3 times as long)