¥ For individual subject
thresholded activation maps:
H Use GLSQ/REML estimation, especially for
slow block design experiments at 3+
Tesla
H Be aware that there may be many false
negatives
o i.e., false
acceptances of the null hypothesis
o am looking
into an FDR-like procedure for estimating the false negative rate, similar to how FDR
estimates the false positive rate
¥ For group maps using ANOVA (or similar
statistics):
H Differences between OLSQ and GLSQ
estimation are small
¥ Recommendations:
H DonÕt need to re-visit group activation conclusions!
H Use 3dREMLfit as a near drop-in replacment for 3dDeconvolve for future work
oA little extra CPU time (usually from 1..3 times as
long)