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¥3dfractionize does this resolution conversion:
¥
å3dfractionize  -template func+orig
å       -input ROI_high_res+orig
å       -clip 0.5 -preserve -prefix ROI_low_res
H-template func+orig ¨ The destination grid you want your ROI grid to be resampled to (weÕre going from high to low resolution here).  Our output dataset ROI_low_res+orig will be written at the resolution of func+orig
H-input ROI_high_res+orig ¨ Defines the input high-resolution dataset (that needs to be converted from high resolution to low resolution)
H-clip 0.5 ¨ Output voxels will only get a nonzero value if they are at least 50% filled by nonzero input voxels (you decide the percentage here). E.g., when going from high to low res, keep a label a voxel as part of the ROI if it is filled with at least 50% (or more) of the voxel value.  For example:
This voxel is 80% filled with the ROI value -- keep it
This voxel is 30% filled with the ROI value -- lose it