¥Data Preparation: Smoothing
HSpatial variability of both FMRI and the Talairach transform can result in little or no overlap of function between subjects.
åData smoothing is used to reduce this problem.
íLeads to loss of spatial resolution, but that is a price to be paid with the Talairach transform
åIn principle, smoothing should be done on time series data, before data fitting (i.e., before 3dDeconvolve or 3dNLfim, etc.)
íOtherwise one has to decide on how to smooth statistical parameters.
ÈIn statistical data sets, each voxel has a multitude of different parameters associated with it like a regression coefficient, t-statistic, F-statistic, etc.
ÈCombining some statistical parameters across voxels might result in parameters with unknown distributions
íBlurring is done using 3dmerge with the -1blur_fwhm option
íBlurring on the surface is done with program SurfSmooth