PowerPoint Presentation - Surface-Based Cross-Subject Analysis

7/2/2004 SSCC/NIMH 2

Geometry and Topology

•Geometry: Spatial location

–X,Y,Z coordinates of brain structures

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•Topology: Spatial connectivity

–Relative positions of brain structures along the surface

•Geometric proximity does not imply topological proximity

–If you care about the topology of activation, you should transfer FMRI data onto the surface before spatial manipulations of the data