> I'm interested in assessing whether behavioral variable B (can be continuous
> or dichotomous) mediates the association between variable A (dichotomous)
> and connectivity with my ROIs of interest. Is this something that AFNI can handle?
So your model is the following?
Connectivity = a0 + b1 * A + b2 * B + b3 * A * B + e
By "connectivity with my ROIs of interest" do you mean that you have run multiple analyses each of which corresponds to one ROI as a seed?
> Also, I am interested in comparing three groups' resting-state
> connectivity with a specific seed region. It looks like I can
> run this analysis with 3dttest++ if I only have 2 groups, but it's
> unclear which program is best for 3 groups. 3dMEMA?
3dttest++, 3dMEMA, and 3dANOVA all can handle multiple groups, but 3dANOVA is the easiest one.
Gang