Hello,
I am attempting to implement the PPI pipeline described
here and have a few questions:
1. I am assuming it is appropriate to use preprocessed data (with some detrending/filtering/normalization already applied) - is this correct?
2. Is the 3dSynthesize/3dCalc method now recommended in place of 3dDetrend?
3. To confirm, If 3dSynthesize is preferred, should one still include the motion and nuisance regressors in the final 3dDeconvolve step even though they are included in 3dSynthesize/3dCalc?
4. A bit off topic - when conducting timecourse analyses (or simply plotting averaged timecourses such as % signal change) is it advisable to first use 3dSynthesize/3dCalc? Or is the original preprocessed data better?
Thank you very much!