> Would I still use PPI if I'm not interested in a specific task condition
> (i.e. I wouldn't be looking at connectivity of an ROI for a contrast between
> two conditions)?
PPI, in its typical usage, explores the interaction between a seed region and the rest of the brain under one condition or the contrast of two conditions.
> The simple correlation analysis indicated that it could be used for both rest and task.
With both rest and tasks, simple correlation would show the overall signal similarity between a seed region and other regions during both rest and all tasks in the experiment. Such an overall measure seems very vague because of the mixture of rest and tasks.
Gang