Hi all

I have been working with a collaborator who preproced (motion correction and normalization) data in SPM. I then transformed them into AFNI format using the following command lines:

to3d -anat -prefix Anat Anat_00001.hdr for the structural
and
to3d -time:zt 46 324 2500 alt+z -prefix Run1 swa_Run1*.hdr
for the functional

The files created got the extension +orig instead of +tlrc and I thought it would not matter (although they were normalized in SPM).

I then processed the data using 3ddeconvolve and the individual data look fine.
However, I ran a ttest on 12 subjects and the group data is not impressive...
The result of 3dFWHM shows a spatial blurring of 20 mm! and I wonder if this means that the data are simply very variable or if it's due to some problem related to the +orig extension instead of +tlrc... (maybe an anat parent confusion as well?).

Did anyone run into that problem before? I would very much appreciate your advice on this topic, thank you very much!

Barbara