AFNI Message Board

Dear AFNI users-

We are very pleased to announce that the new AFNI Message Board framework is up! Please join us at:

https://discuss.afni.nimh.nih.gov

Existing user accounts have been migrated, so returning users can login by requesting a password reset. New users can create accounts, as well, through a standard account creation process. Please note that these setup emails might initially go to spam folders (esp. for NIH users!), so please check those locations in the beginning.

The current Message Board discussion threads have been migrated to the new framework. The current Message Board will remain visible, but read-only, for a little while.

Sincerely, AFNI HQ

History of AFNI updates  

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July 10, 2013 05:27PM
I don't have your mask here, but a back-of-the-envelope calculation with the following script,

3dClustSim -nxyz 39 39 40 -dxyz 3 3 3 -fwhm 6

shows the following table:

# CLUSTER SIZE THRESHOLD(pthr,alpha) in Voxels
# -NN 1 | alpha = Prob(Cluster >= given size)
# pthr | 0.100 0.050 0.020 0.010
# ------ | ------ ------ ------ ------
0.020000 55.7 62.8 71.4 78.7
0.010000 35.1 39.6 45.2 50.0
0.005000 24.5 27.4 31.8 35.3
0.002000 16.6 18.7 21.5 23.6
0.001000 12.8 14.6 16.9 18.7
0.000500 10.1 11.6 13.5 14.9
0.000200 7.6 8.8 10.4 11.7
0.000100 6.0 7.2 8.7 9.8

So it looks like you need a minimum cluster size of 28 voxels to survive the threshold of cluster level significance of 0.05.

However, since you blurred the original data by 6mm FWHM, the real spatial correlation would be most likely greater than 6mm. With a wild guess of 8mm, you may need a minimum cluster size of 51 voxels:

3dClustSim -nxyz 39 39 40 -dxyz 3 3 3 -fwhm 8

# CLUSTER SIZE THRESHOLD(pthr,alpha) in Voxels
# -NN 1 | alpha = Prob(Cluster >= given size)
# pthr | 0.100 0.050 0.020 0.010
# ------ | ------ ------ ------ ------
0.020000 103.4 116.1 133.6 146.5
0.010000 64.2 72.9 84.2 91.8
0.005000 44.0 50.2 58.9 64.5
0.002000 29.2 33.4 39.1 43.6
0.001000 22.0 25.7 30.1 33.8
0.000500 17.3 20.2 24.0 26.5
0.000200 12.8 15.1 18.1 20.3
0.000100 10.2 12.3 15.1 16.6

Gang
Subject Author Posted

Multiple comparisons

patrick July 10, 2013 03:48PM

Re: Multiple comparisons

gang July 10, 2013 05:27PM

Re: Multiple comparisons

patrick July 10, 2013 06:03PM

Re: Multiple comparisons

nick July 11, 2013 04:45AM

Re: Multiple comparisons

patrick July 11, 2013 10:02AM

Re: Multiple comparisons

rick reynolds July 11, 2013 10:17AM

Re: Multiple comparisons

patrick July 11, 2013 02:35PM

Re: Multiple comparisons

rick reynolds July 11, 2013 02:56PM