In the current study in my lab, we are having a difficult time obtaining significant results from a group analysis of older adults. We have examined the data in multiple ways and have come to the conclusion that there is definitely per-subject activation but when the subjects are grouped, the variability in the data results in zero significant clusters. I understand that in order to find significance, there must be many people with activation in the same region, but how do we examine the data of older adults who are likely recruiting various brain regions to complete a task?

Any suggestions would be greatly appreciated!

Thanks!