afni.nimh.nih.gov

No, I would not call that safer, just slightly different.
I was giving reasons why the results might not be
exactly the same. But they should be close.

If the results are very different, then either there is
some mistake or the analysis is on the edge in some
bad way. And if so, you would rather understand why.

For me, if the subject did not leave the scanner, I
would probably analyze it with one command.

- rick