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Thanks Ziad,

I need to perform a "set of noise removal algos" to each of the slices and then combine it as a volume.
Can you please help me in converting 2D slices into a 3D volume ?
These slices are obtained from a volume itself and after performing some operations ( change in pixel values by noise removal ) on each slice , these need to rejoin in order to form a volume without getting its orientation affected.