1). The command I'm using is:
3dfractionize -template anat+orig -input ROI+tlrc -warp tlrc_anat+tlrc -prefix ROI -clip 0.2 -preserve
2). I created a group-level ROI on the MNI space, and I was trying the align this single ROI back to each subject's original space. So I was just wondering if alignment will fail for this case?