Hi AFNI experts,
My question is about when it is appropriate to map data to the surface for resting-state analysis. I am following example 11 from the afni_proc.py help, but I would like to know what the advantages or disadvantages are to mapping the data to the surface before the regress steps or after the regress steps. The dataset I am working with is from a patient population and I am interested in individual differences in connectivity and how it relates to cognitive performance. For example, if I map to the surface before the regress steps, my afni_proc.py command would look like that pasted below. Is there any drawback to this approach vs. waiting until after the regress steps to map to the surface?
afni_proc.py -subj_id p01
-blocks despike tshift align volreg surf blur mask regress
-copy_anat /PATH/p01_SurfVol
-anat_follower_ROI aaseg anat /PATH/fs/SUMA/aparc.a2009s+aseg_rank.nii
-anat_follower_ROI aeseg epi /PATH/fs/SUMA/aparc.a2009s+aseg_rank.nii
-anat_follower_ROI p01vente epi /PATH/fs/SUMA/p01_vent.nii
-anat_follower_ROI p01WMe epi /PATH/fs/SUMA/p01_white.nii
-anat_follower_erode p01vente p01WMe
-dsets /PATH/nameOfFile.HEAD
-surf_anat /PATH/fs/SUMA/p01_SurfVol+orig
-surf_spec /PATH/fs/SUMA/std.141.p01_?h.spec
-volreg_align_to MIN_OUTLIER
-volreg_align_e2a
-blur_size 6
-regress_ROI_PC p01vente 3
-regress_anaticor_fast
-regress_anaticor_label p01WMe
-regress_censor_motion 0.2
-regress_censor_outliers 0.1
-regress_apply_mot_types demean deriv
-regress_run_clustsim no
Thanks in advance,
Kara