Greetings Dear AFNIstas--

With the advent of @SSWarper in addition to some tricks with zero-padding and centering that you've kindly provided, the quality of alignment between our BOLD and anatomical data has improved dramatically. The approaches you've provided are also robust. For data from a 1500-subject, 15-site data consortium with which we collaborate, data from 13 of 15 sites went from average Dice coeffs of ~0.78 to ~0.92. Really nice. This is not to mention even greater improvements in Dice coeffs for warped anatomical to template.

We wonder, then, if you might have suggestions for how we might improve alignment in our two straggler sites? Perhaps there is something instructive in these deviants that might help further improve the techniques you've provided? If you can provide us with an upload link, we'll be happy to share from each site a representative subject's data in addition to the afni_proc script we're currently running.

Yours,

Paul