afni.nimh.nih.gov

Hello,

Would you provide more detail on what you want?

For example, if the problem is that the mean is zero, it would be simple to pre-compute the mean (3dTstat -mean) and add it back in later (3dcalc -a TIME_SERIES -b mean -expr a+b). However, that should not have any effect on computations of functional activation.

So exactly how do you plan to compute the functional activation for the ROIs after 3dTproject? Neither correlations nor regressions should be affected by the zero-mean data.

- rick