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August 09, 2020 10:41AM
Hello!

I had a quick question about registering 4D data to 3D data. I am trying to register a dsc nifti file to a t1 post contrast. In actuality I am registering the dsc data to a t2 that has been already registered to the t1+C because this usually gives better results. However, because I am using a 3D image as the reference, I am losing the 4th dimension of my dsc data. In effect only 1 timepoint is being registered to the structural image. I'm not sure how to go about fixing this. I have included the function I applied and the change in the nifti header matrix that occurs during the transformation. The two datasets have already been skull stripped.

align_epi_anat.py -dset1 dsc_strip.nii.gz -dset2 t2_strip_post.nii.gz -dset1to2 -dset1_strip None -dset2_strip None -suffix _post
3dAFNItoNIFTI dsc_strip_post+orig.

Preregistration dsc nifti header
data_type FLOAT32
dim1 128
dim2 128
dim3 19
dim4 1
datatype 16
pixdim1 1.875000
pixdim2 1.875000
pixdim3 4.000000
pixdim4 0.000000
cal_max 0.0000
cal_min 0.0000
file_type NIFTI-1+

Postregistration dsc nifti header
data_type INT16
dim1 128
dim2 128
dim3 19
dim4 120
datatype 4
pixdim1 1.875000
pixdim2 1.875000
pixdim3 4.000000
pixdim4 1.500000
cal_max 0.0000
cal_min 0.0000
file_type NIFTI-1+

Any help would be greatly appreciated! Thank you so much!
Samantha
Subject Author Posted

4D to 3D Registration Question

SamG August 09, 2020 10:41AM

Re: 4D to 3D Registration Question

Daniel Glen August 09, 2020 01:47PM

Re: 4D to 3D Registration Question

SamG August 09, 2020 03:19PM

Re: 4D to 3D Registration Question

Daniel Glen August 09, 2020 04:50PM