Hi Rick and Paul!

Thank you for all the tips!

I did try the latest AFNI version and the QC report is indeed even more helpful!.. Unfortunately, the Coef+stat images are also only showing diffuse speckles here and there. ; ( [I'm absolutely certain the subject didn't fall asleep and did the task correctly.]

I've tried running instacorr, but setting the seed doesn’t work for me. Nothing obvious happens when I click on "InstaCorr Set". When I try to set the seed overlay in the "FIM→Pick Ideal" menu, there isn't a A_ICOR.1D file.

Re: the stimulus times, the first unadjusted stimulus event time is at 2s.. then at 7s, 12s, 17s etc. So, if I remove 4TRs (=8s), I would remove the first 2 times (at 2s and 7s) and adjust all subsequent times by subtracting 8s, i.e. 12s would become 4s, 17s would become 9s etc. Is that the correct way of doing it?

Cheers,
Misho