> If I want to compare the modulation of response to condition 1 vs condition 2 on the group level (a contrast of
> condition1[1] - condition2[1] ) do I need to adjust the way the AM events on the individual level are being de-meaned?
As "condition1[1] - condition2[1]" is the slope effect, it would have no impact as to whether to demean the modulation variable or how to de-mean it.
Gang