Hi,
Recently, i came across a paper which decribed a method called the Inter Repition Variance analysis. The BOLD signal change associated with activation is detected based only on the frequency of stimulus. So instead of estimating a fit to the data, look at consistency of response upon stimulus as the measure of statistical activation.
I'd imagine that this method would fall apart in the presence of multiple stimuli, but i expect it to work well for a simple case.
Does AFNI support a similar feature?
Thanks,
Shantanu