Bob,
Many people estimate volume from the midsag x-section, but I plan to try to calculate actual volume. I'm sure I'll have to make some determination as to how I define the CC relative to white-matter bundles of the left/right hemis. Not sure exactly how just yet.
I like your idea of making my own CC atlas. I think I can figure that out. Eventually, I'll want the volumes in Talairach space because I've got children and adults in the data set and need a normalized space to compare. Can I just use the CC average atlas to start drawing in Talairach without reverse warping to +orig? Or is it best to calculate in +orig, then transform to Talairach for volume comparison?
Thanks loads.
Jodene