Hello Saori,


Saori Tanaka wrote:

> Dear all,
>
> I'm just trying ROI analysis, and now I use the estimated time
> course using
> finite impulse response model as the averaged BOLD signal
> change in SPM
> (PSTH plot).

So I gather you have been successfully using SPM to analyze your data ...
>
> Although I read some papers using AFNI in showing the averaged
> BOLD signal
> change, I'm not familiar with AFNI.
>
> As far as I can understand, these two methods (SPM and AFNI)
> are very similar
> in estimating BOLD signal change.

SPM and AFNI are quite different in many ways. Although you can do linear regression modeling with both of them. However the interface and implementation of the methods can differ significantly. It is impossible to answer your question concisely (and in an unbiased manner). Better to go through the websites for SPM and AFNI and look at their demos and descriptions so that you can make up your mind about what to use.


>
> Please explain me the differences between these methods, and
> advantages of
> AFNI in showing averaged BOLD signal change.
>

cheers,
-ziad

> Thanks,
>
> Saori Tanaka
>