Hi all,
Here is a question about the principle of fmri and AFNI also.
During the process of parameter estimating, do AFNI presume that all voxels’ hemodynamic response of the brain have the same distribution, and fit the hrf by the same function?
Then, there are two voxels, for example, A and B. Voxel A’s hrf are just normal as most of the cases. Voxel B’s, however, don’t. That means that the signal have an early suppression, or initial dip, which will influence the form of the hrf. This will exert some effects on the estimated results?
Thanks!
-- Chunming Lu