Question is: How should regressors be scaled ?
Lets assume a simple block design, convolved with a
simple gamma HRF as provided by waver.
Let's further assume that we want to use the beta-weights and the
intercept estimate to give us percent change, as in 100*beta/intercept.
Obviously, this will only work with 1 particular scaling of the regressor.
Two options: scale the regressor so that the peak is = 1 or
scale the regressor so that its integral is 1.0
Keith Worsley, in fmristat, does the latter. Here is a quote for how
he calculates is double gamma HRF:
"The final hrf is: gamma1/max(gamma1)-DIP*gamma2/max(gamma2) scaled so that its total integral is 1."
But if I want to get percent change at the peak of the response, using 100*beta/intercept, don't I need to have the peak == 1 ?
If I use waver with -peak 1 will that give me a peak of 1.0, an integral of 1.0 or
what?
Lee