> how much of an impact using the pen as '01,' instead of '012' would have on
> the PPI analysis, esp. on the accuracy of the deconvolution of the seed
> timeseries. I can't really compare since I currently can't run it with 012.
There is probably no such a uniform penalty function or/and penalty factor that would render a reasonable deconvolution result. So the best you can do is to check the result and see if it looks reasonable to you since you know your stimulus timing.
> what about just rounding up the 1/10s to 1s in my 1D files so that I don't
> need to upsample my seed timeseries (TR=2) so much?
Well, try it out and see if it turns out good enough.
Gang