Hello,
So I have 4 conditions (2x2 design) of interest in my experiment. First I averaged the Beta weights of these 4 conditions for each subj and then ran a t-test on these averaged maps to keep only those task-related areas. I then threshold at the voxel (p=0.001) and cluster (n>11 voxels from Alphasim output), and end up with a map of activated areas (mask) of about 10 000 voxels.
Then I use 3dANOVA3 to determine how these 4 conditions modulate the MRI signal in that mask.
My question is what kind of voxel and cluster threshold do I have to implement here. Can I be more liberal on the voxel threshold since I already restricted my search area? Do I have to run alphasim on the mask to determine the number of voxels in a cluster?
Any thoughts is welcome!!
Thanks for you help,