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Daniel, thank you for your kind answer!

I think using 3dcalc in order to extract values of each hemi of a cluster/roi (so I could enter them in ANOVA and test for independent_variable x hemisphere interaction) would do for me.

So, say you wanted to extract right-hemi value of a cluster, would something like this also work?:

"3dcalc -a cluster+tlrc -dicom -expr 'ispositive(x-0)' -prefix right"

The example above was one of very earlier posts, so I wasn't sure whether it was still valid..

Thanks!