BRIKS are apparently being byte-swapped when they are saved after Talairach markers are defined. Here's the sequence of operations:
Load a structural image into the underlay.
Define the 6 markers under the "Define Markers" menu
View as AC-PC aligned and Talairach view.
Images appear to be byte-swapped
Save using the "Write Ulay" button under Datamode.
The original and acpc aligned images are written with the actual byte ordering swapped relative the the header.
Swapping bytes with the command "2swap T1High+org" fixes the problem.
The problem occurs using afni version 2009_12_31_1431 with the 64-bit osx build of 2/1/2010.
I can reliably make the talairach view byte-swap, but I can't reliably get it to write byte-swapped data. That is probably because I rarely use this feature.
This is a very low priority issue for us, but I thought you would like to know if it is in fact a bug.
John