Dear AFNI experts,
I have a naive question about ANOVA with uneven sample sizes. My design is a 2 (patients vs. control) by 2 (young vs. old) factor design, and both factors are between-subject. In addition, the four groups have unequal number of subjects. I have ran several t-tests to examine the Age effect and the Disease effect. But now I want to see the interaction between Age and Disease and feel confused about the program that I can use. I think one simple solution is to use the same sample size in all conditions and run 3dANOVA3. But I really don't want to delete data because of this. Could you please give me any advice? Thank you very much!
Best,
Jie