AFNI Message Board

Dear AFNI users-

We are very pleased to announce that the new AFNI Message Board framework is up! Please join us at:

https://discuss.afni.nimh.nih.gov

Existing user accounts have been migrated, so returning users can login by requesting a password reset. New users can create accounts, as well, through a standard account creation process. Please note that these setup emails might initially go to spam folders (esp. for NIH users!), so please check those locations in the beginning.

The current Message Board discussion threads have been migrated to the new framework. The current Message Board will remain visible, but read-only, for a little while.

Sincerely, AFNI HQ

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S
August 06, 2015 02:10PM
I am interested in running a mediation analysis to test whether the association between variable A (continuous behavioral variable) and whole-brain functional connectivity of seed region B is mediated by continuous behavioral variable C while controlling for factors such as movement, age, and gender.
Previous posts on the discussion board have suggested that 3dttest++ can handle this analysis.
To accomplish this end, could you please confirm that 3dttest++ should be run with each subject's z-scored whole-brain connectivity map with seed region B as inputs and Variable A and Variable C entered as covariates?

If so, could you please clarify how to interpret the output?
To get the main effects of each behavioral factor (A & C) independently, would a separate 3dttest++ need to be run without the other variable (A or C)?

Thank you!
S
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Resting-state Mediation

S August 06, 2015 02:10PM

Re: Resting-state Mediation

gang August 07, 2015 11:45AM