afni.nimh.nih.gov

Hi Paul-

My inclination is to recommend Option 1, compute a summary statistic and then use that for your prediction. I think the variability of using all of the data points is going to make classification difficult. I can't promise that RSFC measures will be the answer, but that seems like a better option than all of the issues you may have using "raw" time series.

Happy to discuss more though!

-Peter