Hi Rick,
Thanks again! I gave this a try with RAM of 20x the size of the data set (2.6TB for about 130GB of data) and had the same issue about 20 seconds into the job. I can't find any indications that the process is running out of RAM (e.g., no complaints from SLURM, the cluster's scheduler, for exceeding the requested memory). I'm in touch with the HPC team, but I can't see any indications that the problem is with requesting that much RAM on our cluster. I recently ran a job that used 960GB of RAM on the same node and there's 3TB of RAM available on that node. Is it possible it could be an AFNI issue?
Dillon