Hi-

Important to note is that the colin brain is NOT an average brain atlas, it is a single brain atlas and is the reason that you can get a surface template from the colin brain using Freesurfer, Caret, BrainVoyager, etc. As you say, average brain atlas's are problematic for surface reconstruction, so I am not aware of any tools that will create a surface reconstruction of an average brain like the CCHMC or the MNI. The Van Essen Lab has created an population surface-based atlas of 12 normal adult brains, called PALS, that is valuable (http://sumsdb.wustl.edu:8081/sums/index.jsp) for surface-based analysis. To do this, they created surface reconstructions of 12 individual volumes and then averaged them together. We are going to use it for our 6 yo data set, because with Caret, unlike with Freesurfer, you use only 6 core(most stable) landmarks to register individual brains to the atlas. We think
this will give us good surface-based morphometry results. Also important to note, before using Caret, we do register the individual volumes to the CCHMC_young atlas using FSL FLIRT.

That said, I too would like to see a children's population surface-based atlas. There is a need for this.

Best,
Veronica

Research Engineer
University of Washington Neuroimaging Research Group



On Thu, 2 Mar 2006 phorum@afni.nimh.nih.gov wrote:

> This message was sent by Anthony Dick from: AFNI Message Board.
> [afni.nimh.nih.gov]
> ----------------------------------------------------------------
>
> Hello-
>
> The problem is that the child template is very blurry and will not run
> through freesurfer (it won't inflate because there is so little contrast
> between grey and white matter). We think this is because it is an average.
> We are wondering how other averages (e.g., Colin brain) were processed and
> made available as surface templates.
>
> Thanks again.
>
> Anthony
>
> ----------------------------------------------------------------
> Sent using Phorum software version 3.4.8a [phorum.org]
>

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