Hi Paul,

Thanks for your input!

Great regarding the cluster sizes and that I have got the correct sources for citation!

Regarding running two 1-sided t-tests: We almost always use the 2-sided tables that are generated from clustsim. Perhaps we can get away with a 1-sided on some of our tasks but we have chosen to basically always use 2-sided since we are interesed in differencies in both directions. Hope that sounds reasonable.

Yeah "Q3" wasn't really a question. It was just to illustrate that we agree that it is unreasonable to throw away findings that e.g. is one voxel from surviving or are only significant with an alpha of 0.06-7, especially if it is a bileteral finding in predicted areas. My point though, was that it might be tricky with some reviewers since we can't, even though it is close, write that the finding is FWE corrected within AFNI because what we can cite is only the three sources above and they call for a p-value no larger than 0.002. And I can't really cite a discussion like this. So now we are thiking about how to phrase thse situations in upcoming manuscripts without downlplaying the finding too much. A finding that might be a false negative since the method is kind of conservative (at least that is our experience so far).



Edited 1 time(s). Last edit at 02/14/2019 12:54PM by Robin.