Hi Gang,

No, I don't want to compare the 4 runs. Each subject was scanned for two resting state sessions (REST 1 and REST 2) over a period of two days. During each session, data were collected using both the left-right (LR) and right-left (RL) phase-encoding runs. I want to treat the 4 runs (REST1 LR, REST1 RL, REST2 LR, REST2 RL) as 1 run. I initially tried to concatenate the 4 epi files into 1 file prior to proc py but pt and Rick suggested me to run proc py separately. So I'll have 4 Fischer transformed seed-based correlation volumes (REST1 LR, REST1 RL, REST2 LR, REST2 RL) after preprocessing and I was not sure how to submit them into group analysis. I was wondering if it is possible that group analysis programs (3dttest or 3dLME) take multiple runs per subject, or do they only take one run per subject. Could you please clarify this?

Best,
JW