Thanks for providing a clear context.

> a little more emphasis is placed on type II error compared to fMRI in the research arena but type I error is still of significant concern

We probably all agree that it would make more sense to keep some kind of balance between the two sides of the coin. I don't have any definite suggestion to your question, but I would like to say that the statistical information extracted from the data is dependent on several factors: the quality of the data, the amount of data (e.g., samples), experimental design, etc. There is always some extent of uncertainty involved. Regardless of the methodology you decide to adopt to combine the three maps, it might be better to present the three separate maps, together with the combined final result, in a gradated fashion, not a dichotomized/thresholded one. In doing so, the surgeon can combine all sources of information, not only the statistics but also anatomical information plus expertise, before making the final judgment.

Gang



Edited 3 time(s). Last edit at 03/30/2022 11:36AM by Gang.