AFNI Message Board

Dear AFNI users-

We are very pleased to announce that the new AFNI Message Board framework is up! Please join us at:

https://discuss.afni.nimh.nih.gov

Existing user accounts have been migrated, so returning users can login by requesting a password reset. New users can create accounts, as well, through a standard account creation process. Please note that these setup emails might initially go to spam folders (esp. for NIH users!), so please check those locations in the beginning.

The current Message Board discussion threads have been migrated to the new framework. The current Message Board will remain visible, but read-only, for a little while.

Sincerely, AFNI HQ

History of AFNI updates  

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February 09, 2009 03:47PM

By the way, is your data scaled to a mean of 100? It seems to be...

So your regression is presumably for a single run with a quadratic baseline,
and 3 regressors of interest. That suggests that you are running waver but
not using the '-peak 1' option, which you should consider using to scale the
regressors (and therefore the betas) to mean a percent change.

As a separate thought, you stated that regressor C is baseline. Are you
actually modeling the baseline with that third regressor? If so, there may
be multicollinearity in your design matrix, since the basline is already
modeled as a quadratic polynomial (or you have 3 runs of constant baseline).

---

After all that babbling, let me try to address your initial question.
Your three betas of interest are very small in the precuneus (wherever that
is... :), relative to those from the ACC. None of the points that have been
brought up address that, even multicolinearity.

Since they are _relatively_ small, how you are scaling things really does
not matter (unless regressors were scaled very differently say, which does
not appear to be the case). And even if you were modeling the baseline in
multiple ways (such as if A+B+C = constant), that would still have to come
out with A, B and C canceling each other by being bigger than they should
be, perhaps with opposite signs. Since they are all small, that is not the
case either.

So it looks to me like that average response there is simply small. One way
that can happen is if your fixation stimulus also activates the region, and
so it is active for the entire run. Or perhaps it is a very small region (I
*could* look it up, but that would take seconds), and you have applied a large
blur which bleeds it away.

That's all that comes to mind at the moment.

- rick

Subject Author Posted

Mean beta values

Woogul Lee February 09, 2009 11:15AM

Re: Mean beta values

rick reynolds February 09, 2009 11:27AM

Re: Mean beta values

Woogul Lee February 09, 2009 02:02PM

Re: Mean beta values

Woogul Lee February 09, 2009 02:04PM

Re: Mean beta values

rick reynolds February 09, 2009 02:37PM

Re: Mean beta values

Woogul Lee February 09, 2009 02:50PM

Re: Mean beta values

rick reynolds February 09, 2009 03:47PM

Re: Mean beta values

Woogul Lee February 09, 2009 05:13PM

Re: Mean beta values

rick reynolds February 09, 2009 06:40PM

Re: Mean beta values

Woogul Lee February 10, 2009 03:54PM

Re: Mean beta values

rick reynolds February 10, 2009 06:27PM

Re: Mean beta values

Woogul Lee February 10, 2009 07:08PM

Re: Mean beta values

rick reynolds February 11, 2009 09:38AM

Re: Mean beta values

Woogul Lee February 11, 2009 02:20PM