Hello AFNI users and makers,
I am wondering what the best way is to look for differences in IRFs between subjects and between groups. I'm estimating IRFs to a stimulus using a TENT(0,14,8) model in 3ddeconvolve. What is the best way to produce an average IRF for a group of subjects and compare that average IRF to the average IRF from another group?
Would it be appropriate to average each IRF time point's beta value (the data has previously been converted to % change from the voxel-wise mean rather than absolute intensity) across the subjects in a group to come up with a group average IRF? Would it be better to fit a curve to each subject's IRF estimate and then find average values for the curve fit parameters for the group? Is there a completely different method that is typically used?
Thanks,
-John