AFNI Message Board

Dear AFNI users-

We are very pleased to announce that the new AFNI Message Board framework is up! Please join us at:

https://discuss.afni.nimh.nih.gov

Existing user accounts have been migrated, so returning users can login by requesting a password reset. New users can create accounts, as well, through a standard account creation process. Please note that these setup emails might initially go to spam folders (esp. for NIH users!), so please check those locations in the beginning.

The current Message Board discussion threads have been migrated to the new framework. The current Message Board will remain visible, but read-only, for a little while.

Sincerely, AFNI HQ

History of AFNI updates  

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April 08, 2020 04:52PM
Well it depends on the details, of course. Nonlinear warping is often done for distortion correction. So things like blip-up/blip-down distortion and B0 field map correction require computing a nonlinear warp to apply to the EPI data. A single nonlinear warp is applied to all the EPI volumes equally for the purpose. Often this is combined with affine transformation for motion correction and for alignment to a corresponding anatomical dataset. Additionally, affine and nonlinear warps are concatenated and applied to bring the processsed data into a standard template space.

Usually we compute an affine alignment between the EPI data and the anatomical data. Is the result not good at that step of the alignment? Or are you not seeing good alignment of the anatomical dataset to a template? There we do use a nonlinear warp to align the data to the template. You can potentially increase the weighting for some areas or allow for more distortion. Or do separate analyses with different alignments. The cerebellum is a bit trickier thant other areas because it hangs very differently from one person to another. That sometimes makes a separate cerebellum analysis necessary. Jorn Diedrichsen made a separate cerebellum template and atlas for this purpose.

We generally do not apply a different nonlinear warp for the purpose of motion correction though. For this to work at all, you need to have exceptionally good structural resolution. I've tried something similar in the past, and I've seen best performance visually with an inilev and maxlev both set to 4, so no big warps and no tiny warps. That was for that particular data, and your data will be different. In the end, we decided against it, because there is still some arbitrary warping inside areas that have little visible structure in the EPI data.
Subject Author Posted

nonlinear warping epi to anat

Simone Cauzzo April 07, 2020 05:07PM

Re: nonlinear warping epi to anat

Daniel Glen April 08, 2020 04:52PM

Re: nonlinear warping epi to anat

Simone Cauzzo April 08, 2020 06:45PM

Re: nonlinear warping epi to anat

Daniel Glen April 09, 2020 09:12AM

Re: nonlinear warping epi to anat

Simone Cauzzo April 09, 2020 05:12PM