Hi Andrew,
Indeed, the coordinates 0,0,0 are far outside that anat+orig
dataset. And if the stats do not overlay in orig space, they
will not overlay after the +tlrc transformation.
I see the data came via the NIfTI format, written by FSL.
You will probably need to go back into FSL and see where the
appropriate coordinate system was lost. Maybe that applies
to your stats dataset, too.
You can start with the output of the sform from nifti_tool:
nifti_tool -disp_nim -field sto_xyz -infiles aanp_005_Anat_T1W_3D_FFE_SENSE_FSL_3_1.nii
- rick